Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).

Addition of poly(ADP-ribose) (PAR) is an important post-translational modification in higher eukaryotes. Several DNA repair and checkpoint proteins possess specific PAR-binding zinc-finger (PBZ) modules critical for function. Here, we present solution structures of the two PBZ modules of aprataxin a...

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Những tác giả chính: Eustermann, S, Brockmann, C, Mehrotra, P, Yang, J, Loakes, D, West, S, Ahel, I, Neuhaus, D
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2010