Kinetic parameters of human aspartate/asparagine-β-hydroxylase suggest that it has a possible function in oxygen sensing

Human aspartate/asparagine-β-hydroxylase (AspH) is a 2-oxoglutarate (2OG) dependent oxygenase that catalyzes the post-translational hydroxylation of Asp- and Asn-residues in epidermal growth factor-like domains (EGFDs). Despite its biomedical significance, studies on AspH have long been limited by a...

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Manylion Llyfryddiaeth
Prif Awduron: Brewitz, L, Tumber, A, Schofield, CJ
Fformat: Journal article
Iaith:English
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020