MicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay.

microRNAs (miRNAs) represent a novel class of genome-encoded eukaryotic regulatory RNAs that silence gene expression posttranscriptionally. Although the proteins mediating miRNA biogenesis and function have been identified, the precise mechanism by which miRNAs regulate the expression of target mRNA...

Full description

Bibliographic Details
Main Authors: Behm-Ansmant, I, Rehwinkel, J, Izaurralde, E
Format: Journal article
Language:English
Published: 2006