What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit.

The GRIA1 locus, encoding the GluA1 (also known as GluRA or GluR1) AMPA glutamate receptor subunit, shows genome-wide association to schizophrenia. As well as extending the evidence that glutamatergic abnormalities have a key role in the disorder, this finding draws attention to the behavioural phen...

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Bibliographic Details
Main Authors: Barkus, C, Sanderson, D, Rawlins, J, Walton, M, Harrison, P, Bannerman, D
Format: Journal article
Language:English
Published: 2014