CRAC channels drive digital activation and provide analog control and synergy to Ca(2+)-dependent gene regulation.

Ca(2+)-dependent gene expression is critical for cell growth, proliferation, plasticity, and adaptation [1-3]. Because a common mechanism in vertebrates linking cytoplasmic Ca(2+) signals with activation of protein synthesis involves the nuclear factor of activated T cells (NFAT) family of transcrip...

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Bibliografiska uppgifter
Huvudupphovsmän: Kar, P, Nelson, C, Parekh, A
Materialtyp: Journal article
Språk:English
Publicerad: 2012