A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.

The jumonji (JMJ) family of histone demethylases are Fe2+- and α-ketoglutarate-dependent oxygenases that are essential components of regulatory transcriptional chromatin complexes. These enzymes demethylate lysine residues in histones in a methylation-state and sequence-specific context. Considerabl...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Kruidenier, L, Chung, C, Cheng, Z, Liddle, J, Che, K, Joberty, G, Bantscheff, M, Bountra, C, Bridges, A, Diallo, H, Eberhard, D, Hutchinson, S, Jones, E, Katso, R, Leveridge, M, Mander, P, Mosley, J, Ramirez-Molina, C, Rowland, P, Schofield, C, Sheppard, R, Smith, J, Swales, C, Tanner, R, Thomas, P
Materialtyp:	Journal article
Språk:	English
Publicerad:	2012

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.

Liknande verk