Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA.

In addition to double- and single-strand DNA breaks and isolated base modifications, ionizing radiation induces clustered DNA damage, which contains two or more lesions closely spaced within about two helical turns on opposite DNA strands. Post-irradiation repair of single-base lesions is routinely...

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Bibliographic Details
Main Authors: Dianov, G, O'Neill, P, Goodhead, D
Format: Journal article
Language:English
Published: 2001