Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex.
Numerous top-down kinetic models have been constructed to describe the cell cycle. These models have typically been constructed, validated and analyzed using model species (molecular intermediates and proteins) and phenotypic observations, and therefore do not focus on the individual model processes...
Main Authors: | , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2010
|