Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements.

The transcriptional mechanism through which chondrocytes control the spatial and temporal composition of the cartilage tissue has remained largely elusive. The central aim of this study was to identify whether transcriptional enhancers played a role in the organisation of the chondrocytes in cartila...

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Bibliographic Details
Main Authors: Li, I, Liu, K, Neal, A, Clegg, P, De Val, S, Bou-Gharios, G
Format: Journal article
Language:English
Published: Nature Publishing Group 2018