Single cell RNA sequencing reveals molecular and functional platelet bias of aged hematopoietic stem cells

Aged hematopoietic stem cells (HSCs) generate more myeloid cells and fewer lymphoid cells compared to young HSCs, contributing to decreased adaptive immunity in aged individuals. However, it is not known how intrinsic changes to HSCs and shifts in the balance between biased HSC subsets each contribu...

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Bibliographic Details
Main Authors:	Nerlov, C, Grover, A, Giustacchini, A, Gambardella, A, Macaulay, I, Mead, A, Jacobsen, S, Sanjuan-Pla, A, Thongjuea, S, Carrelha, J, Mancini, E, Luis, T
Format:	Journal article
Published:	Nature Publishing Group 2016

Single cell RNA sequencing reveals molecular and functional platelet bias of aged hematopoietic stem cells

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