LGI1, CASPR2 and related antibodies: a molecular evolution of the phenotypes

LGI1, CASPR2 and related antibodies: a molecular evolution of the phenotypes

Recent biochemical observations have helped redefine antigenic components within the voltage-gated potassium channel (VGKC) complex. The related autoantibodies may be now divided into likely pathogenic entities, which target the extracellular domains of leucine-rich glioma-inactivated 1 (LGI1) and c...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Binks, S, Klein, C, Waters, P, Pittock, S, Irani, S
Μορφή:	Journal article
Έκδοση:	BMJ Publishing Group 2017

Παρόμοια τεκμήρια

The immunogenetics of LGI1- and CASPR2-antibody encephalitis: towards aetiology
ανά: Binks, S
Έκδοση: (2022)

Distinct HLA associations of LGI1 and CASPR2-antibody diseases
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Έκδοση: (2018)

Magnetic resonance imaging characteristics of LGI1-antibody and CASPR2-antibody encephalitis
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Έκδοση: (2024)

CXCL13 levels in LGI1-and CASPR2-autoantibody syndromes
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Έκδοση: (2019)

Immunotherapy responsive neuropathic pain associated with LGI1 and CASPR2 antibodies
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Έκδοση: (2021)

Stop testing for autoantibodies to the VGKC-complex: only request LGI1 and CASPR2
ανά: Michael, S, κ.ά.
Έκδοση: (2020)

Phenotypic Spectrum of CASPR2 and LGI1 Antibodies Associated Neurological Disorders in Children
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Έκδοση: (2022-04-01)

Hippocampal epileptogenesis in LGI1, CASPR2 and GABABR antibodies: preliminary findings
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Έκδοση: (2020)

Randomized placebo‐controlled trial of intravenous immunoglobulin in autoimmune LGI1/CASPR2 epilepsy
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Έκδοση: (2019)

Randomized placebo‐controlled trial of intravenous immunoglobulin in autoimmune LGI1/CASPR2 epilepsy
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Έκδοση: (2019)

The distinct pattern of movement disorders in Caspr2 and LGI1 antibody associated autoimmune encephalitis
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Έκδοση: (2019)

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Έκδοση: (2017)

Vgkc is dead: long live lgi1- and caspr2-antibodies. intracellular and non-neuronal targets of voltage-gated potassium channel complex antibodies
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Έκδοση: (2020)

LGI1 and CASPR2-related Morvan syndrome - diagnostic challenges in a pediatric case
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Έκδοση: (2023-06-01)

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Έκδοση: (2014-05-01)

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Antibody Properties Associate with Clinical Phenotype in LGI1 Encephalitis
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Έκδοση: (2023-01-01)

Reply to: Hemichorea Associated with CASPR2 Antibody
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Cognitive, neuropsychiatric and quality-of-life sequelae in LGI1-antibody disease demonstrates fatigue as the key determinant of wellbeing
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‘Less contented as a person’: preliminary data from the LGI1-QoL study
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Έκδοση: (2017)

LGI1 expression and human brain asymmetry: insights from patients with LGI1-antibody encephalitis
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Έκδοση: (2018-09-01)

CASPR2 antibody associated neurological syndromes in children
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Έκδοση: (2023-02-01)

‘Less contented as a person’: an update from the LGI1-QoL study
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Έκδοση: (2019)

Immunotherapy-responsive chorea as the presenting feature of LGI1-antibody encephalitis.
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Έκδοση: (2012)

Intrathecal B cell activation in LGI1-antibody encephalitis
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Έκδοση: (2020)

LGI1-antibody encephalitis is characterised by frequent, multifocal clinical and subclinical seizures
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Έκδοση: (2017)

Investigating B cell biology in CASPR2-antibody encephalitis
ανά: Sun, B
Έκδοση: (2022)

Efficacy of Tocilizumab in Limbic Encephalitis with Anti-CASPR2 Antibodies
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Έκδοση: (2020-01-01)

CXCL13 levels and autoantibody epitope specificities in LGI1-autoantibody syndromes
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Έκδοση: (2019)

LGI1-antibody associated epilepsy successfully treated in the outpatient setting
ανά: Uribe-San-Martín, R, κ.ά.
Έκδοση: (2020)

Clonal hematopoiesis in LGI1‐antibody encephalitis
ανά: Soo Jean Shin, κ.ά.
Έκδοση: (2024-10-01)

Improving clinical practice with an old friend from the neuroimmunology toolkit: acute corticosteroids in LGI1 antibody encephalitis
ανά: Irani, SR
Έκδοση: (2021)

Antibodies to the Caspr1/contactin-1 complex in chronic inflammatory demyelinating polyneuropathy
ανά: Pascual-Goni, E, κ.ά.
Έκδοση: (2021)

CIELO: a randomized, double-blind, placebo-controlled, phase 3 basket study of satralizumab in patients with NMDAR- or LGI1-antibody encephalitis
ανά: Gelfand, JM, κ.ά.
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Characterization of cardiac bradyarrhythmia associated with LGI1-IgG autoimmune encephalitis
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