Reprogramming the immune system: co-receptor blockade as a paradigm for harnessing tolerance mechanisms.
SUMMARY: The challenge of harnessing tolerance as a therapeutic modality has been greatly influenced by dogmas dictating how self-tolerance comes about. Deletional strategies popularized from the classical work of Medawar and Owen have always demanded stringent attention to eliminating all antigen-r...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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