Vaccinia virus immunomodulator A46: A lipid and protein-binding scaffold for sequestering host TIR-domain proteins.

Vaccinia virus immunomodulator A46: A lipid and protein-binding scaffold for sequestering host TIR-domain proteins.

Vaccinia virus interferes with early events of the activation pathway of the transcriptional factor NF-kB by binding to numerous host TIR-domain containing adaptor proteins. We have previously determined the X-ray structure of the A46 C-terminal domain; however, the structure and function of the A46...

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Bibliografiske detaljer
Main Authors:	Fedosyuk, S, Bezerra, G, Radakovics, K, Smith, T, Sammito, M, Bobik, N, Round, A, Ten Eyck, L, Djinović-Carugo, K, Usón, I, Skern, T
Andre forfattere:	Fremont, D
Format:	Journal article
Sprog:	English
Udgivet:	Public Library of Science 2016

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