Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.

Dehydroepiandrosterone sulphate (DHEAS) is the most abundant circulating steroid secreted by adrenal glands--yet its function is unknown. Its serum concentration declines significantly with increasing age, which has led to speculation that a relative DHEAS deficiency may contribute to the developmen...

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Main Authors:	Zhai, G, Teumer, A, Stolk, L, Perry, JR, Vandenput, L, Coviello, A, Koster, A, Bell, J, Bhasin, S, Eriksson, J, Eriksson, A, Ernst, F, Ferrucci, L, Frayling, T, Glass, D, Grundberg, E, Haring, R, Hedman, A, Hofman, A, Kiel, D, Kroemer, H, Liu, Y, Lunetta, K, Maggio, M, Lorentzon, M, Mangino, M, Melzer, D, Miljkovic, I, Nica, A, Penninx, B, Vasan, R, Rivadeneira, F, Small, K, Soranzo, N, Uitterlinden, A, Völzke, H, Wilson, S, Xi, L, Zhuang, W, Harris, T, Murabito, J, Ohlsson, C, Murray, A, de Jong, F, Spector, T, Wallaschofski, H, Perry, J
Format:	Journal article
Language:	English
Published:	Public Library of Science 2011

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.

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