Sister chromatid cohesion establishment during DNA replication termination

Newly copied sister chromatids are tethered together by the cohesin complex, but how sister chromatid cohesion is coordinated with DNA replication is poorly understood. Prevailing models suggest cohesin complexes, bound to DNA before replication, remain behind the advancing replication fork to keep...

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Bibliographic Details
Main Authors: Cameron, G, Gruszka, DT, Gruar, R, Xie, S, Kaya, Ç, Nasmyth, KA, Baxter, J, Srinivasan, M, Yardimci, H
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2024