Restricted processing of glycans by endomannosidase in mammalian cells.

Removal of α-glucose residues from nascent glycoproteins in the early secretory pathway is a requirement for further N-glycan maturation. Although deglucosylation is a stepwise process mediated by endoplasmic reticulum-associated glucosidases I and II for most glycoproteins, Golgi endo-α-mannosidase...

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Bibliographic Details
Main Authors: Kukushkin, N, Easthope, I, Alonzi, D, Butters, T
Format: Journal article
Language:English
Published: 2012