Restricted processing of glycans by endomannosidase in mammalian cells.
Removal of α-glucose residues from nascent glycoproteins in the early secretory pathway is a requirement for further N-glycan maturation. Although deglucosylation is a stepwise process mediated by endoplasmic reticulum-associated glucosidases I and II for most glycoproteins, Golgi endo-α-mannosidase...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2012
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