Non-image-forming light driven functions are preserved in a mouse model of autosomal dominant optic atrophy

Autosomal dominant optic atrophy (ADOA) is a slowly progressive optic neuropathy that has been associated with mutations of the OPA1 gene. In patients, the disease primarily affects the retinal ganglion cells (RGCs) and causes optic nerve atrophy and visual loss. A subset of RGCs are intrinsically p...

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Bibliographic Details
Main Authors: Perganta, G, Barnard, A, Katti, C, Vachtsevanos, A, Douglas, R, Maclaren, R, Votruba, M, Sekaran, S
Format: Journal article
Language:English
Published: Public Library of Science 2013