Non-image-forming light driven functions are preserved in a mouse model of autosomal dominant optic atrophy
Autosomal dominant optic atrophy (ADOA) is a slowly progressive optic neuropathy that has been associated with mutations of the OPA1 gene. In patients, the disease primarily affects the retinal ganglion cells (RGCs) and causes optic nerve atrophy and visual loss. A subset of RGCs are intrinsically p...
Main Authors: | Perganta, G, Barnard, A, Katti, C, Vachtsevanos, A, Douglas, R, Maclaren, R, Votruba, M, Sekaran, S |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2013
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