Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction.

The aging process in the hippocampus is associated with aberrant epigenetic marks, such as DNA methylation and histone tail alterations. Recent evidence suggests that caloric restriction (CR) can potentially delay the aging process, while upregulation of antioxidants may also have a beneficial effec...

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Bibliographic Details
Main Authors: Chouliaras, L, van den Hove, D, Kenis, G, Draanen, M, Hof, P, van Os, J, Steinbusch, H, Schmitz, C, Rutten, B
Format: Journal article
Language:English
Published: 2013