Maturing human CD127+ CCR7+ PDL1+ dendritic cells express AIRE in the absence of tissue restricted antigens

Expression of the Autoimmune regulator (AIRE) outside of the thymus has long been suggested in both humans and mice, but the cellular source in humans has remained undefined. Here we identify AIRE expression in human tonsils and extensively analyzed these “extra-thymic AIRE expressing cells” (eTACs)...

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Bibliografiske detaljer
Main Authors: Fergusson, JR, Morgan, MD, Bruchard, M, Huitema, L, Heesters, BA, Van Unen, V, Van Hamburg, JP, Van Der Wel, NN, Picavet, D, Koning, F, Tas, SW, Anderson, MS, Marioni, JC, Holländer, GA, Spits, H
Format: Journal article
Udgivet: Frontiers Media 2019