Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons

Parkinson's disease (PD) is the second most common neurodegenerative disorder and a central role for α-Synuclein (αSyn; SNCA) in disease aetiology has been proposed based on genetics and neuropathology. To better understand the pathological mechanisms of αSyn, we generated induced pluripotent s...

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Бібліографічні деталі
Автори: Zambon, F, Cherubini, M, Fernandes, HJR, Lang, C, Ryan, BJ, Volpato, V, Bengoa-Vergniory, N, Vingill, S, Attar, M, Booth, HDE, Haenseler, W, Vowles, J, Bowden, R, Webber, C, Cowley, SA, Wade-Martins, R
Формат: Journal article
Мова:English
Опубліковано: Oxford University Press 2019

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