A functional misexpression screen uncovers a role for enabled in progressive neurodegeneration

Drosophila is a well-established model to study the molecular basis of neurodegenerative diseases. We carried out a misexpression screen to identify genes involved in neurodegeneration examining locomotor behavior in young and aged flies. We hypothesized that a progressive loss of rhythmic activity...

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Bibliografische gegevens
Hoofdauteurs: Rezával, C, Berni, J, Gorostiza, E, Werbajh, S, Fagilde, M, Fernández, M, Beckwith, E, Aranovich, E, Sabio Y García, C, Ceriani, M
Formaat: Journal article
Taal:English
Gepubliceerd in: Public Library of Science 2008