Involvement of metallothionein (MT) as a biological protective factor against carcinogenesis induced by benzo[a]pyrene (B[a]P).

The purpose of this study was to examine whether intracellular metallothionein (MT) protects against benzo[a]pyrene (B[a]P)-induced forestomach and lung carcinogenesis. Ten-week-old male MT-I/II null mice and wild-type mice were orally administered B[a]P at a dose of 100 or 250 mg/kg twice a week fo...

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Bibliographic Details
Main Authors: Takaishi, M, Shimada, A, Suzuki, J, Satoh, M, Nagase, H
Format: Journal article
Language:English
Published: 2010