Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules

Purpose: MHC class I presentation of peptides allows T cells to survey the cytoplasmic protein milieu of host cells. During infection, presentation of self peptides is, in part, replaced by presentation of microbial peptides. However, little is known about the self peptides presented during infectio...

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Bibliographic Details
Main Authors: Spencer, CT, Bezbradica, JS, Ramos, MG, Arico, CD, Conant, SB, Gilchuk, P, Gray, JJ, Zheng, M, Niu, X, Hildebrand, W, Link, AJ, Joyce, S
Format: Journal article
Language:English
Published: Wiley 2015