Membrane phase-dependent occlusion of intramolecular GLUT1 cavities demonstrated by simulations

Experimental evidence has shown a close correlation between the composition and physical state of the membrane bilayer and glucose transport activity via the glucose transporter GLUT1. Cooling alters the membrane lipids from the fluid to gel phase, and also causes a large decrease in the net glucose...

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Détails bibliographiques
Auteurs principaux: Iglesias-Fernandez, J, Quinn, P, Naftalin, R, Domene, C
Format: Journal article
Langue:English
Publié: Elsevier 2017