Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia

Genetic lesions such as BCR-ABL1, E2A-PBX1, and MLL rearrangements (MLLr) are associated with unfavorable outcomes in adult B-cell precursor acute lymphoblastic leukemia (B-ALL). Leukemia oncoproteins may directly or indirectly disrupt cytosine methylation patterning to mediate the malignant phenoty...

Täydet tiedot

Bibliografiset tiedot
Päätekijät:	Geng, H, Brennan, S, Milne, T, Chen, W, Li, Y, Hurtz, C, Kweon, S, Zickl, L, Shojaee, S, Neuberg, D, Huang, C, Biswas, D, Xin, Y, Racevskis, J, Ketterling, R, Luger, S, Lazarus, H, Tallman, MS, Rowe, J, Litzow, MR, Guzman, M, David Allis, C, Roeder, R, Müschen, M, Paietta, E
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2012

Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Tekijä Geng, H, Brennan, S, Milne, T, Chen, W, Li, Y, Hurtz, C, Kweon, S, Zickl, L, Shojaee, S, Neuberg, D, Huang, C, Biswas, D, Xin, Y, Racevskis, J, Ketterling, R, Luger, S, Lazarus, H, Tallman, MS, Rowe, J, Litzow, MR, Guzman, M, Allis, C, Roeder, R, Müschen, M, Paietta, E

Julkaistu 2012

Journal article

Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia

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