Computational studies of ligand binding to TRIM PHD-bromodomains
<p>Modulating the function of epigenetic reader domains such as bromodomains (BRDs) and plant homeodomains (PHD), which bind acetylated lysine and methylated lysine respectively, has the potential to alter disease-associated epigenetic states. TRIM24 and TRIM33 are members of the tripartite mo...
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Format: | Thesis |
Language: | English |
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2023
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