Computational studies of ligand binding to TRIM PHD-bromodomains

<p>Modulating the function of epigenetic reader domains such as bromodomains (BRDs) and plant homeodomains (PHD), which bind acetylated lysine and methylated lysine respectively, has the potential to alter disease-associated epigenetic states. TRIM24 and TRIM33 are members of the tripartite mo...

Full description

Bibliographic Details
Main Author: Lee, B
Other Authors: Duarte Gonzalez, F
Format: Thesis
Language:English
Published: 2023
Subjects: