Characterization and immunogenicity of a Shigella flexneri 2a O-antigen bioconjugate vaccine candidate

Shigellosis remains a major cause of diarrheal disease in developing countries and causes substantial morbidity and mortality in children. Vaccination represents a promising preventive measure to fight the burden of the disease, but despite enormous efforts, an efficacious vaccine is not available t...

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Bibliographic Details
Main Authors: Ravenscroft, N, Braun, M, Schneider, J, Dreyer, A, Wetter, M, Haeuptle, M, Kemmler, S, Steffen, M, Sirena, D, Herwig, S, Carranza, P, Jones, C, Pollard, A, Wacker, M, Kowarik, M
Format: Journal article
Language:English
Published: Oxford University Press 2019