Too weak for biophysics: Prioritising and progressing fragment hits from X-ray crystallographic screening.
<p>In the last decade, X-ray crystallography has matured to a powerful primary screening technique for fragment hit identification in structure-based drug discovery. Unmatched in its sensitivity, it provides valuable knowledge of precise fragment binding location in a protein-fragment complex....
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Format: | Thesis |
Language: | English |
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2021
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