Genomic reconstruction by serial mitotic recombination of yeast artificial chromosomes.
DNA cloned in yeast artificial chromosomes (YACs) is a valuable resource for functional experiments in cell culture as well as whole animal systems. Where the size or chimerism of a YAC clone are limiting factors it may be desirable to generate recombinant YAC clones. One such approach is based on m...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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