Investigating TDP43 biological dysfunction through the characterisation of Tardbp ENU mouse mutants: implications for neurodegeneration
<p>TDP43 is a highly conserved ubiquitously expressed protein which performs multiple roles in RNA metabolism, including regulation of gene expression, pre-mRNA splicing and the regulation of micro-RNA biogenesis. It belongs to the hnRNP family and interacts extensively with other proteins and...
| Main Authors: | , |
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| Format: | Thesis |
| Language: | English |
| Published: |
2014
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| Subjects: |