Investigating TDP43 biological dysfunction through the characterisation of Tardbp ENU mouse mutants: implications for neurodegeneration
<p>TDP43 is a highly conserved ubiquitously expressed protein which performs multiple roles in RNA metabolism, including regulation of gene expression, pre-mRNA splicing and the regulation of micro-RNA biogenesis. It belongs to the hnRNP family and interacts extensively with other proteins and...
Hlavní autoři: | , |
---|---|
Další autoři: | |
Médium: | Diplomová práce |
Jazyk: | English |
Vydáno: |
2014
|
Témata: |