Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

The Fanconi anemia (FA) pathway plays a central role in the repair of DNA interstrand crosslinks (ICLs) and regulates cellular responses to replication stress. Homologous recombination (HR), the error-free pathway for double-strand break (DSB) repair, is required during physiological cell cycle prog...

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Bibliographic Details
Main Authors: Michl, J, Zimmer, J, Tarsounas, M
Format: Journal article
Language:English
Published: EMBO Press 2016