Enhanced Efficacy of the CDNF/MANF Family by Combined Intranigral Overexpression in the 6-OHDA Rat Model of Parkinson's Disease.

Cerebral Dopamine Neurotrophic Factor (CDNF) and Mesencephalic Astrocyte-derived Neurotrophic factor (MANF) are members of a recently discovered family of neurotrophic factors (NTFs). Here, we used intranigral or intrastriatal lentiviral vector-mediated expression to evaluate their efficacy at prote...

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Bibliographic Details
Main Authors: Cordero-Llana, O, Houghton, B, Rinaldi, F, Taylor, H, Yáñez-Muñoz, R, Uney, J, Wong, L, Caldwell, M
Format: Journal article
Language:English
Published: Nature Publishing Group 2014