Stability and Dynamics of Membrane-Spanning DNA Nanopores

Recently developed DNA-based analogues of membrane proteins advance synthetic biology. A fundamental question is how hydrophilic nanostructures reside in the hydrophobic environment of the membrane. Here we use multiscale molecular dynamics (MD) simulations to explore the structure, stability and dy...

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Bibliographic Details
Main Authors: Maingi, V, Burns, J, Uusitalo, J, Howorka, S, Marrink, S, Sansom, M
Format: Journal article
Published: Springer Nature 2017