GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome (MDS)

Inherited gene variants play an important role in malignant diseases. The transcriptional repressor Growth factor independence 1 (GFI1) regulates hematopoietic stem cell (HSC) self-renewal and differentiation. A single nucleotide polymorphism of GFI1 (rs34631763) generates a protein with an asparagi...

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Detalhes bibliográficos
Principais autores:	Botezatu, L, Michel, L, Makishima, H, Schroeder, T, Germing, U, Haas, R, van der Reijden, B, Marneth, A, Bergevoet, S, Jansen, J, Przychodzen, B, Wlodarski, M, Niemeyer, C, Platzbecker, U, Ehninger, G, Unnikrishnan, A, Beck, D, Pimanda, J, Hellström-Lindberg, E, Cazzola, M, Malcovati, L, Boultwood, J, Pellagatti, A, Papaemmanuil, E, Le Coutre, P, Kaeda, J, Opalka, B, Möröy, T, Dührsen, U, Maciejewski, J, Khandanpour, C
Formato:	Journal article
Idioma:	English
Publicado em:	Elsevier 2016

GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome (MDS)

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