Plasma pharmacokinetics of once- versus twice-daily lamivudine and abacavir: simplification of combination treatment in HIV-1-infected children (PENTA-13).

Plasma pharmacokinetics of once- versus twice-daily lamivudine and abacavir: simplification of combination treatment in HIV-1-infected children (PENTA-13).

BACKGROUND: There are few data on plasma and intracellular pharmacokinetics (PK) of once-daily (q24h) nucleoside analogues in HIV-infected children. METHODS: Children aged 2-13 years receiving combination treatment containing lamivudine (3TC) (4 mg/kg) and/or abacavir (ABC) (8 mg/kg) twice daily (q1...

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Bibliographic Details
Main Authors:	Bergshoeff, A, Burger, D, Verweij, C, Farrelly, L, Flynn, J, Le Prevost, M, Walker, S, Novelli, V, Lyall, H, Khoo, S, Gibb, D
Format:	Journal article
Language:	English
Published:	2005

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