Recognition of GT mismatches by Vsr mismatch endonuclease.
The Vsr mismatch endonuclease recognises the sequence CTWGG (W = A or T) in which the underlined thymine is paired with guanine and nicks the DNA backbone on the 5'-side of the mispaired thymine. By using base analogues of G and T we have explored the functional groups on the mismatch pair whic...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2000
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