Parallel changes of proinsulin and islet amyloid polypeptide in glucose intolerance.

Elevated proinsulin secretion and islet amyloid deposition are both features of Type 2 diabetes but their relationship to beta-cell dysfunction is unknown. To determine if islet amyloid polypeptide (IAPP) secretion is disproportionate with other beta-cell products at any stage of glucose intolerance...

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Bibliographic Details
Main Authors: MacNamara, C, Barrow, B, Manley, SE, Levy, J, Clark, A, Turner, R
Format: Journal article
Language:English
Published: 2000