Parallel changes of proinsulin and islet amyloid polypeptide in glucose intolerance.

Parallel changes of proinsulin and islet amyloid polypeptide in glucose intolerance.

Elevated proinsulin secretion and islet amyloid deposition are both features of Type 2 diabetes but their relationship to beta-cell dysfunction is unknown. To determine if islet amyloid polypeptide (IAPP) secretion is disproportionate with other beta-cell products at any stage of glucose intolerance...

Полное описание

Библиографические подробности
Главные авторы:	MacNamara, C, Barrow, B, Manley, SE, Levy, J, Clark, A, Turner, R
Формат:	Journal article
Язык:	English
Опубликовано:	2000

Схожие документы

Proinsulin is sensitive to reflect glucose intolerance
по: Akinobu Nakamura, и др.
Опубликовано: (2020-01-01)

Pancreatic islet amyloid and elevated proinsulin secretion in familial maturity-onset diabetes.
по: Clark, A, и др.
Опубликовано: (1987)

Autoantibodies to islet amyloid polypeptide in diabetes.
по: Clark, A, и др.
Опубликовано: (1991)

Islet amyloid polypeptide gene promoter polymorphisms are not associated with Type 2 diabetes or with the severity of islet amyloidosis.
по: Esapa, C, и др.
Опубликовано: (2005)

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology
по: Rehana Akter, и др.
Опубликовано: (2016-01-01)

Fibrillar dimer formation of islet amyloid polypeptides
по: Chi-cheng Chiu, и др.
Опубликовано: (2015-09-01)

Islet amyloid polypeptide does not suppress pancreatic cancer
по: Austin J. Taylor, и др.
Опубликовано: (2023-02-01)

Studies on alpha-synuclein and islet amyloid polypeptide interaction
по: Ye Wang, и др.
Опубликовано: (2023-01-01)

The Effect of Cholesterol on Membrane-Bound Islet Amyloid Polypeptide
по: Mikkel Christensen, и др.
Опубликовано: (2021-04-01)

Normal proinsulin responses to glucose in mild type II subjects with subnormal insulin response.
по: Levy, J, и др.
Опубликовано: (1993)

The effect of islet amyloid polypeptide (amylin) and calcitonin gene-related peptide on glucose removal in the anaesthetized rat and on insulin secretion from rat pancreatic islets in vitro.
по: Tedstone, A, и др.
Опубликовано: (1990)

Study of islet amyloid polypeptide aggregation and its inhibition mechanisms.
по: Wei, Lei.
Опубликовано: (2011)

The molecular basis of distinct aggregation pathways of islet amyloid polypeptide
по: Chan-Park, Mary B., и др.
Опубликовано: (2012)

Mechanistic Contributions of Biological Cofactors in Islet Amyloid Polypeptide Amyloidogenesis
по: Phuong Trang Nguyen, и др.
Опубликовано: (2015-01-01)

Electrochemical Assay of Human Islet Amyloid Polypeptide and Its Aggregation
по: Genxi Li, и др.
Опубликовано: (2008-09-01)

Dynamics of the formation of a hydrogel by a pathogenic amyloid peptide: islet amyloid polypeptide
по: Vaux, D, и др.
Опубликовано: (2016)

Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo
по: Xiao-Dan Mo, и др.
Опубликовано: (2018-03-01)

Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide
по: Zhi-Xue Xu, и др.
Опубликовано: (2016-01-01)

Human islet amyloid polypeptide oligomers stabilized and probed by MAS NMR
по: Ziwei Chang, и др.
Опубликовано: (2024-02-01)

Identification of Human Islet Amyloid Polypeptide as a BACE2 Substrate.
по: Ingrid C Rulifson, и др.
Опубликовано: (2016-01-01)

The Mitochondrial Peptidase Pitrilysin Degrades Islet Amyloid Polypeptide in Beta-Cells.
по: Hanjun Guan, и др.
Опубликовано: (2015-01-01)

Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation.
по: Saraogi, I, и др.
Опубликовано: (2010)

The role of the cellular membrane environment in mediating fibrillization and toxicity of islet amyloid polypeptide
по: Carmen, H
Опубликовано: (2016)

Interaction of Human Resistin with Human Islet Amyloid Polypeptide at Charged Phospholipid Membranes
по: Susanne Dogan, и др.
Опубликовано: (2022-06-01)

Drosophila melanogaster as a model system for studies of islet amyloid polypeptide aggregation.
по: Sebastian Wolfgang Schultz, и др.
Опубликовано: (2011-01-01)

Association of Islet Amyloid Polypeptide and Inflammatory Markers in Type 2 Diabetes Mellitus
по: Zunjarrao Ganpat Badade, и др.
Опубликовано: (2021-06-01)

Islet amyloid polypeptide & amyloid beta peptide roles in Alzheimer’s disease: two triggers, one disease
по: Sofia Ferreira, и др.
Опубликовано: (2021-01-01)

Insulin and islet amyloid polypeptide 'amylin' form stable molecular complexes in vitro affecting fibril formation
по: Clark, A, и др.
Опубликовано: (1999)

RESTING THE BETA-CELLS WITH INSULIN IN NIDDM DOES NOT IMPROVE BETA-CELL FUNCTION NOR PROINSULIN PROCESSING
по: Rachman, J, и др.
Опубликовано: (1995)

Fluorinated triazolamers: preferential conformations and activities on islet amyloid polypeptide (hIAPP) aggregation
по: Ongeri, Sandrine, и др.
Опубликовано: (2025-02-01)

Zinc and pH modulate the ability of insulin to inhibit aggregation of islet amyloid polypeptide
по: Samuel D. McCalpin, и др.
Опубликовано: (2024-06-01)

Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide
по: Cristina Nuñez-Diaz, и др.
Опубликовано: (2023-02-01)

Zinc and iron dynamics in human islet amyloid polypeptide-induced diabetes mouse model
по: Ayako Fukunaka, и др.
Опубликовано: (2023-03-01)

Islet Amyloid Polypeptide: A Partner in Crime With Aβ in the Pathology of Alzheimer's Disease
по: Ana F. Raimundo, и др.
Опубликовано: (2020-03-01)

Contribution of the 12–17 hydrophobic region of islet amyloid polypeptide in self-assembly and cytotoxicity
по: Mathilde Fortier, и др.
Опубликовано: (2022-10-01)

Levels of islet amyloid polypeptide in cerebrospinal fluid and plasma from patients with Alzheimer's disease.
по: Nina Schultz, и др.
Опубликовано: (2019-01-01)

Optimized experimental pre-treatment strategy for temporary inhibition of islet amyloid polypeptide aggregation
по: Madison Q. Ferguson, и др.
Опубликовано: (2021-07-01)

Chaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpression.
по: Lisa Cadavez, и др.
Опубликовано: (2014-01-01)

Conformations of islet amyloid polypeptide monomers in a membrane environment: implications for fibril formation.
по: Mojie Duan, и др.
Опубликовано: (2012-01-01)

UDP-glucose, cereblon-dependent proinsulin degrader
по: Jaeyong Cho, и др.
Опубликовано: (2022-08-01)