Cryo-EM of soft-landed β-galactosidase: gas-phase and native structures are remarkably similar

Native mass spectrometry (MS) has become widely accepted in structural biology, providing information on stoichiometry, interactions, homogeneity, and shape of protein complexes. Yet, the fundamental assumption that proteins inside the mass spectrometer retain a structure faithful to native proteins...

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Bibliographic Details
Main Authors: Esser, T, Boehning, J, Oenuer, A, Chinthapalli, DK, Eriksson, L, Grabarics, M, Fremdling, P, Konijnenberg, A, Makarov, A, Botman, A, Peter, C, Benesch, J, Robinson, C, Gault, J, Baker, L, Bharat, TAM, Rauschenbach, S
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2024