Cryo-EM of soft-landed β-galactosidase: gas-phase and native structures are remarkably similar
Native mass spectrometry (MS) has become widely accepted in structural biology, providing information on stoichiometry, interactions, homogeneity, and shape of protein complexes. Yet, the fundamental assumption that proteins inside the mass spectrometer retain a structure faithful to native proteins...
Main Authors: | , , , , , , , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
American Association for the Advancement of Science
2024
|