Glucocorticoids inhibit osteoblast proliferation via transcriptional upregulation of MKP-1: A prime target for the development of novel osteo-anabolic agents

Glucocorticoids inhibit osteoblast proliferation via transcriptional upregulation of MKP-1: A prime target for the development of novel osteo-anabolic agents

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Hulley, P, Horsch, K, De Wet, H, Conradie, M, Langeveldt, C, Hough, F
Μορφή:	Conference item
Έκδοση:	2003

Παρόμοια τεκμήρια

Rapid inhibitory effects of glucocorticoids on ERK activity and osteoblast proliferation occur via transcriptional upregulation of MKP-1
ανά: Horsch, K, κ.ά.
Έκδοση: (2004)

Rapid inhibitory effects of glucocorticoids on ERK activity and osteoblast proliferation occur via transcriptional upregulation of MKP-1
ανά: Horsch, K, κ.ά.
Έκδοση: (2004)

Vanadate protects osteoblasts in vitro and in vivo from glucocorticoid impairment of proliferation
ανά: Hulley, P, κ.ά.
Έκδοση: (2002)

MKP-1 knockout does not prevent glucocorticoid-induced bone disease in mice.
ανά: Conradie, M, κ.ά.
Έκδοση: (2011)

Glucocorticoids induce rapid up-regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and impair proliferation in human and mouse osteoblast cell lines.
ανά: Engelbrecht, Y, κ.ά.
Έκδοση: (2003)

The Role of MKP-1 in the Anti-Proliferative Effects of Glucocorticoids in Primary Rat Pre-Osteoblasts.
ανά: Micheline Sanderson, κ.ά.
Έκδοση: (2015-01-01)

Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo.
ανά: Conradie, M, κ.ά.
Έκδοση: (2007)

Glucocorticoid-induced osteoporosis in the rat is prevented by the tyrosine phosphatase inhibitor, sodium orthovanadate.
ανά: Hulley, P, κ.ά.
Έκδοση: (2002)

Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferation.
ανά: Horsch, K, κ.ά.
Έκδοση: (2007)

The tyrosine phosphatase inhibitor vanadate protects osteoblasts from growth inhibition by glucocorticoids.
ανά: Hulley, P, κ.ά.
Έκδοση: (1999)

Alternative insulin signalling pathways in osteoblasts
ανά: Langeveldt, C, κ.ά.
Έκδοση: (2002)

Alternative insulin signalling pathways in osteoblast cell lines
ανά: Langeveldt, C, κ.ά.
Έκδοση: (2002)

Pharmacological estrogen administration causes a FSH-independent osteo-anabolic effect requiring ER alpha in osteoblasts.
ανά: Sebastian Seitz, κ.ά.
Έκδοση: (2012-01-01)

Glucocorticoid transiently upregulates mitochondrial biogenesis in the osteoblast
ανά: Chien-Ning Hsu, κ.ά.
Έκδοση: (2020-01-01)

The identification of transcriptional targets associated with osteoblast apoptosis signaling in response to growth factor withdrawal
ανά: Liang, M, κ.ά.
Έκδοση: (2006)

Regulation of bim in glucocorticoid-mediated osteoblast apoptosis.
ανά: Espina, B, κ.ά.
Έκδοση: (2008)

The BH3-only protein BIM is upregulated in osteoblasts in response to dexamethasone treatment, growth factor deprivation and anoikis
ανά: Espina, B, κ.ά.
Έκδοση: (2005)

Pathogenesis of glucocorticoid osteoporosis: Role of tyrosine phosphatases
ανά: Hulley, P, κ.ά.
Έκδοση: (2001)

BIM is a novel regulator of glucocorticoid-induced apoptosis in osteoblasts
ανά: Espina, B, κ.ά.
Έκδοση: (2006)

Inhibition of mitogen-activated protein kinase activity and proliferation of an early osteoblast cell line (MBA 15.4) by dexamethasone: role of protein phosphatases.
ανά: Hulley, P, κ.ά.
Έκδοση: (1998)

Bim as a potential target in osteoblast survival
ανά: Espina, B, κ.ά.
Έκδοση: (2005)

OsteoBLAST: Computational Routine of Global Molecular Analysis Applied to Biomaterials Development
ανά: Marcel Rodrigues Ferreira, κ.ά.
Έκδοση: (2020-10-01)

Cynarin attenuates LPS-induced endothelial inflammation via upregulation of the negative regulator MKP-3
ανά: Da Bin Kim, κ.ά.
Έκδοση: (2022-05-01)

Regulation of the CCL2 gene in pancreatic β-cells by IL-1β and glucocorticoids: role of MKP-1.
ανά: Susan J Burke, κ.ά.
Έκδοση: (2012-01-01)

Identification of polymorphisms in the MKP1 gene and their association with bone mineral density in men with asthma
ανά: Bassiti, A, κ.ά.
Έκδοση: (2005)

Scoparone attenuates PD-L1 expression in human breast cancer cells by MKP-3 upregulation
ανά: Seung-Woo Kim, κ.ά.
Έκδοση: (2024-12-01)

Stattns: Potential cartilage anabolics?
ανά: Gennero, I, κ.ά.
Έκδοση: (2004)

Anabolic effects and inhibition of interleukin 6 production induced by neridronate on human osteoblasts
ανά: S. Niccolini, κ.ά.
Έκδοση: (2011-09-01)

Randomness improvement of AES using MKP
ανά: Al-Alak, Saif, κ.ά.
Έκδοση: (2013)

Nonlinearity contributions on critical MKP equation
ανά: H.G. Abdelwahed
Έκδοση: (2020-01-01)

MECHANISMS OF OSTEOBLAST INHIBITION BY STEROIDS
ανά: Hulley, P
Έκδοση: (2004)

Bim is transcriptionally regulated during induction of apoptosis by growth factor withdrawal in osteoblasts
ανά: Liang, M, κ.ά.
Έκδοση: (2007)

Comparison of the Anabolic Effects of Reported Osteogenic Compounds on Human Mesenchymal Progenitor-derived Osteoblasts
ανά: Robert Owen, κ.ά.
Έκδοση: (2020-01-01)

OsteoKnee®
ανά: Lai, K.W.
Έκδοση: (2015)

Role and regulation of MKP-1 in airway inflammation
ανά: Seyed M. Moosavi, κ.ά.
Έκδοση: (2017-08-01)

TBX3 regulates the transcription of VEGFA to promote osteoblasts proliferation and microvascular regeneration
ανά: Lichuang Wu, κ.ά.
Έκδοση: (2022-07-01)

The Unexpected Anabolic Phenotype and Extended Longevity of Skin Fibroblasts after Chronic Glucocorticoid Excess
ανά: Harris Pratsinis, κ.ά.
Έκδοση: (2006-04-01)

Prenatal dexamethasone exposure reduces osteoprogenitor proliferation in mice via histone modifications at the Mkp-1 gene locus
ανά: Yongheng Xie, κ.ά.
Έκδοση: (2024-11-01)

Loss of the PTH/PTHrP receptor along the osteoblast lineage limits the anabolic response to exercise.
ανά: Joseph D Gardinier, κ.ά.
Έκδοση: (2019-01-01)

Identification of a Novel Osteogenetic Oligodeoxynucleotide (osteoDN) That Promotes Osteoblast Differentiation in a TLR9-Independent Manner
ανά: Yuma Nihashi, κ.ά.
Έκδοση: (2022-05-01)