Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope.

Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope.

Cytotoxic T lymphocytes (CTLs) are critical for the control of human immunodeficiency virus, but containment of virus replication can be undermined by mutations in CTL epitopes that lead to virus escape. We analyzed the evolution in vivo of an immunodominant, HLA-A2-restricted CTL epitope and found...

詳細記述

書誌詳細
主要な著者: Iversen, A, Stewart-Jones, G, Learn, G, Christie, N, Sylvester-Hviid, C, Armitage, A, Kaul, R, Beattie, T, Lee, J, Li, Y, Chotiyarnwong, P, Dong, T, Xu, X, Luscher, M, MacDonald, K, Ullum, H, Klarlund-Pedersen, B, Skinhøj, P, Fugger, L, Buus, S, Mullins, J, Jones, E, Van Der Merwe, P, Mcmichael, A
フォーマット: Journal article
言語:English
出版事項: 2006

類似資料