exo-FISH: protocol for detecting DNA breaks in repetitive regions of mammalian genomes

<p>Detecting DNA breaks in defined regions of the genome is critical to advancing our understanding of genome stability maintenance. Here, we present exo-FISH, a protocol to label exposed single-stranded DNA in defined repetitive regions of mammalian genomes by combining <i>in vitro</...

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Bibliographic Details
Main Authors: Saayman, X, Graham, E, Leung, CWB, Esashi, F
Format: Journal article
Language:English
Published: Cell Press 2023