Heterogeneous leukemia stem cells in myeloid blast phase chronic myeloid leukemia
Chronic myeloid leukemia (CML) is an excellent model of the multistep processes in cancer. Initiating BCR-ABL mutations are required for the initial phase of the disease (chronic phase, CP-CML). Some CP-CML patients acquire additional mutation(s) that transforms CP-CML to poor prognosis, hard to tre...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Society of Hematology
2016
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