Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques.

OBJECTIVES: Administration of synthetic long peptides (SLPs) derived from human papillomavirus to cervical cancer patients resulted in clinical benefit correlated with expansions of tumour-specific T cells. Because vaginal mucosa is an important port of entry for HIV-1, we have explored SLP for HIV...

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Bibliographic Details
Main Authors: Rosario, M, Borthwick, N, Stewart-Jones, G, Mbewe-Mvula, A, Bridgeman, A, Colloca, S, Montefiori, D, Mcmichael, A, Nicosia, A, Quakkelaar, E, Drijfhout, J, Melief, C, Hanke, T
Format: Journal article
Language:English
Published: 2012