In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model.

PURPOSE: The monoclonal antibody (mAb) 14C5 is a murine IgG1 directed against a yet undefined molecule involved in cell substrate adhesion found on the surface of malignant breast cancer tissue. mAb 14C5 is able to inhibit cell substrate adhesion and invasion of breast cancer cells in vitro. In nor...

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Bibliographic Details
Main Authors: Burvenich, I, Schoonooghe, S, Cornelissen, B, Blanckaert, P, Coene, E, Cuvelier, C, Mertens, N, Slegers, G
Format: Journal article
Language:English
Published: 2005