MPTP, impairment of motor performance and amine accumulation in Macaca fascicularis.

The selective neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) was injected (IV) into monkeys (Macaca fascicularis) in two different injection regimes. With the small dose regime, one monkey was injected with 0.25 mg/kg, every other day, over a 16 day period. In the large dose regime,...

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Bibliographic Details
Main Authors: Willis, G, Savulescu, J, Horne, M, Smith, G
Format: Journal article
Language:English
Published: 1987