A Multidisciplinary Hyper-Modeling Scheme in Personalized In Silico Oncology: Coupling Cell Kinetics with Metabolism, Signaling Networks, and Biomechanics as Plug-In Component Models of a Cancer Digital Twin

A Multidisciplinary Hyper-Modeling Scheme in Personalized In Silico Oncology: Coupling Cell Kinetics with Metabolism, Signaling Networks, and Biomechanics as Plug-In Component Models of a Cancer Digital Twin

The massive amount of human biological, imaging, and clinical data produced by multiple and diverse sources necessitates integrative modeling approaches able to summarize all this information into answers to specific clinical questions. In this paper, we present a hypermodeling scheme able to combin...

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Bibliographic Details
Main Authors: Kolokotroni, E, Abler, D, Ghosh, A, Tzamali, E, Grogan, J, Georgiadi, E, Büchler, P, Radhakrishnan, R, Byrne, H, Sakkalis, V, Nikiforaki, K, Karatzanis, I, McFarlane, NJB, Kaba, D, Dong, F, Bohle, RM, Meese, E, Graf, N, Stamatakos, G
Format: Journal article
Language:English
Published: MDPI 2024

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